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The Human VEGF Receptor 2/KDR Rapid ELISA Kit quantitates FLK1 (VEGF Receptor 2) in serum and plasma
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors. FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CD309, FLK1, KDR, VEGFR, VEGFR2
基因ID : (Human) 3791
基因符号 : KDR
蛋白别名 : CD309, CD309 antigen, sCD309, soluble CD309, soluble VEGFR 2, VEGF R2, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, tyrosine kinase growth factor receptor, unnamed protein product, Vascular endothelial growth factor receptor 2, VEGFR-2, tyrosine kinase
UniProt ID (Human) P35968