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Human YWHAE quantitates human YWHAE in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human YWHAE.
14-3-3 epsilon belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : 14-3-3E, HEL2, KCIP-1, MDCR, MDS
基因ID : (Human) 7531
基因符号 : YWHAE
蛋白别名 : 14-3-3 epsilon, epididymis luminal protein 2, mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, tyrosine 3/tryptophan 5 -monooxygenase activation protein, unnamed protein product
UniProt ID (Human) P62258