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Developing targeted small molecule quantitative workflows for clinical research presents numerous challenges. From determining optimal methods to enhance selectivity and specificity, to achieving improved detection and quantitation limits, the Thermo Scientific™ Stellar™ mass spectrometer is designed to overcome these obstacles. This revolutionary instrument features a quadrupole mass filter, dual-purpose ion concentrating routing multipole, and a dual-pressure linear ion trap, which collectively expand effective data acquisition schemes and maintain quantitative sensitivity for both large and small molecules.
Join this on-demand webinar to explore key considerations for method development in applied workflows such as toxicology research, fast chromatography, and automated intelligent instrument control. Discover how to leverage higher-energy dissociation (HCD) and resonant collisional dissociation (CID) using tMS² and tMS³ acquisition to enhance quantitative selectivity, sensitivity, and specificity in complex biological matrices.
Courtney Patterson, Masters of Science
Product Specialist in the Clinical Vertical Marketing Group
Thermo Fisher Scientific
Courtney Patterson is an Application Scientist in Clinical and Forensic Toxicology at Thermo Fisher Scientific based out of San Jose, CA. She has a background in forensic toxicology, receiving her master’s in forensic chemistry from The Pennsylvania State University. Her previous role was working as a Forensic Toxicologist for the US Army in their Forensic Toxicology Drug Testing Laboratory (FTDTL) in Fort Meade, MD. Recently, she has been developing fast, quantitative LCMS workflows for drugs of abuse and novel psychoactive substances (NPS) to be utilized by forensic labs in a production setting.
Jingshu Guo, Ph.D
Sr. Product Application Specialist in the Clinical Vertical Marketing Group
Thermo Fisher Scientific
Dr. Jingshu Guo is a trained mass spectrometrist with 10+ years of experience in LC-MS-based qualitative and quantitative analyses of small molecules, nucleosides, peptides, and intact protein. After joining Thermo Fisher Scientific, she worked on the method development, implementation, and optimization in healthcare, clinical and toxicology-related fields. One of her current focuses is to develop fast quantification methods in small molecules, such as biomarkers, therapeutic drugs, and drugs of abuse in biofluids using LC coupled to triple quadrupole MS, ion trap MS, or high-resolution MS, and LC-free MS platforms.