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Empowering your pharmacogenomics (PGx) journey with PGx solutions you can trust
What is pharmacogenomics (PGx)?
Pharmacogenomics, or PGx, is the study of how genes affect a person’s response to drugs. By understanding these genetic variations, researchers can uncover insights that may help prevent adverse drug reactions, improve treatment outcomes, and reduce healthcare costs.
Advancing PGx with proven experience
At Thermo Fisher Scientific, we share your mission to protect human health. Backed by more than two decades of PGx innovation, our comprehensive portfolio of reliable genotyping workflow solutions supports both translational and clinical research.
Technologies designed to fit your PGx workflow
Pharmacogenomics testing depends on precise, reliable technologies to detect genetic variations that influence drug response. Common approaches include real-time PCR (qPCR), microarray, next-generation sequencing (NGS), and digital PCR (dPCR). Together, these technologies form the foundation of scalable, accurate PGx testing workflows for translational and clinical research applications.
What factors are important for your PGx project?
Whether your priority is faster turnaround or broader gene coverage, our complementary portfolio of PGx solutions works together to support your research goals.
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Whether you’re establishing, optimizing, or scaling PGx testing, our experienced team members partner with you to:
- Identify the right workflow solutions for your goals
- Offer guideline-aligned, relevant content
- Enable both fixed-content and customizable panels
- Provide responsive services and technical support
Together, we help you turn genomic data into meaningful discoveries towards advancing precision medicine and improving human health.
Which platform technologies should you choose for your PGx testing program?
Consider panel size: How many pharmacogenes are you planning to include in your assay or panel design?
| Focused panels (single gene testing and up to 10 genes) |
Mid-sized panels (between 10–100 genes) |
Large panels (Over 100 genes) |
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Consider targeted PGx or comprehensive PGx approaches: Compare our PGx platform technologies
Explore our comprehensive portfolio of pharmacogenomics (PGx) solutions, arranged from targeted PGx approaches on the left to comprehensive PGx options on the right:
| Technology/platform | Digital PCR | Real-Time PCR | Targeted NGS | Microarray |
| Products | QuantStudio Absolute Q Digital PCR System | TrueMark PGx SNP + CNV Solution on QuantStudio 5, 7, and 12K Flex real-time PCR systems | Ion AmpliSeq PGx custom panels on Ion GeneStudio S5 systems and the Ion Torrent Genexus Integrated Sequencer | Custom designs and PharmacoPRO / PangenomePRO Plus array plates on SwiftArrayStudio microarray |
| Applications | Multiplexed CNV analysis | SNP and CNV genotyping | SNP and CNV genotyping | SNP and CNV genotyping, HLA and Whole Genome Coverage |
| Highlights |
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| No. of PGx markers | Up to 4 markers | Up to 240 markers | 12–5,000 amplicons (an amplicon can potentially have multiple markers) | 2,000–15,000 or more markers, depending on the array |
| No. of genes | Single gene testing and up to 4 targets multiplexed per assay | Single gene testing and many genes | Customizable (tens to hundreds of genes targeted per panel) | Many genes; coverage is array-dependent |
| Sample volume / throughput per run | 4–16 samples per run | Up to 144 samples per run | Up to 48 samples per run automated on the Genexus System and up to 384 samples per run on the GeneStudio S5 system (manual library prep) | 24 or 96 samples/run |
| Formats | 16 well plate |
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Single tube with multiplexed assays |
24- or 96-well format SBS/ANSI plates |
| Time to results | 90 minutes | <1 day for diplotype results (approx. 8 hours) | 16 hours to 2 days | 30 hours on the SwiftArrayStudio microarray 5 days on the GeneTitan instrument |
| Cost per sample | $$ | $ | $$$ | $$ |
| Request project costs |
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For Research Use Only. Not for use in diagnostic procedures.
