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This compendium of articles on the methods and means to handle chemical or radiological threats in the field examines how chemical, biological, radiological, and nuclear (CBRN) teams, explosive ordinance disposal (EOD) technicians, and other military and defense teams can move from uncertainty to confident action. It explores how the use of advanced portable technologies enables rapid detection of potential hazards, chemical identification, radiological reconnaissance, isotope identification, and personal radiation dose monitoring. For those responding to potentially hazardous unknown conditions, the information in this publication can help support safer decision-making, reduce unnecessary exposure, and maintain mission readiness in high-pressure environments.