Reorienting and Recalibrating: NGS Chimerism Monitoring Post HSCT​

Explore the latest in chimerism detection and monitoring. Dr. Arthi Anand will share insights from her research in chimerism testing, focusing on the impact of sensitivity on chimerism monitoring, detection, early signaling of disease relapse and the interpretation of chimerism numerical values.


Key takeaways
:
  • Understand the Impact of Sensitivity in Chimerism Testing: Gain insights into how sensitivity affects chimerism monitoring and its clinical implications.​

  • Correlate NGS Results with Clinical Changes in Disease Relapse: Understand how small changes can be detected, with different resolution, to correlate NGS results with clinical changes in disease relapse.​

  • Good Concordance with STR: Have confidence in NGS chimerism testing.​

  • Improved Correlation with Clinical Presentation: Data suggests a better correlation with clinical presentation and higher sensitivity, especially when specific lineage cells are utilized.​

  • Faster Turnaround Time: Shorter analysis times enable quicker results, enhancing overall efficiency.​

Guest speaker:
 

Arthi Anand​

H&I Lab Director​

North West London Pathology Consultant Clinical Scientist in H&I, NHS

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