MagMAX CORE Nucleic Acid Purification Kit

Advanced magnetic bead-based solution for high-yield DNA and RNA extraction from non-human samples

Streamline nucleic acid extraction with MagMAX CORE—fast, efficient, and flexible for all types of throughput. As global demands grow, Thermo Fisher Scientific offers end-to-end solutions backed by decades of experience, enabling accurate extraction and analysis across animal-derived, environmental, bacterial, and viral samples.

MagMAX CORE Nucleic Acid Purification Kit benefits

Accelerate	Optimize
Fast instrument processing times, allowing you to achieve results more quickly Premixed washes that don’t require the addition of alcohols Higher-quality nucleic acids, which may lead to less retesting and fewer workflow interruptions Save time and effort by eliminating the need for multiple extraction methods	Complete workflows address 14 unique sample types to simplify the process Single protocol adapted for multiple KingFisher systems Room temperature-stable reagents with a two-year shelf life

Accelerate

Optimize

Fast instrument processing times, allowing you to achieve results more quickly
Premixed washes that don’t require the addition of alcohols
Higher-quality nucleic acids, which may lead to less retesting and fewer workflow interruptions
Save time and effort by eliminating the need for multiple extraction methods

Complete workflows address 14 unique sample types to simplify the process
Single protocol adapted for multiple KingFisher systems
Room temperature-stable reagents with a two-year shelf life

Learn more with our educational resources

Which kit should I use?

	MagMAX CORE Nucleic Acid Purification Kit	MagMAX CORE AgGenomic DNA Extraction Kit
Overview	A versatile and modular technology for nucleic acid purification from diverse animal samples. A versatile and modular technology for nucleic acid purification from diverse animal samples, offering a fast and simple workflow. Uniquely handles up to 14 samples, including hard-to-lyse bacterial samples, with high/low throughput options.	Designed for rapid, high-throughput purification of high-quality genomic DNA from a variety of sample types. The kit uses magnetic bead-based separation and is compatible with KingFisher magnetic particle processors.
Catalog numbers	100 reactions (A32700) 500 reactions (A32702) Mechanical Lysis Module (A32836) Mastitis & Panbacteria Module (A40289)	Made to order
Supported samples	Whole blood; serum; plasma; feces; oral fluid; animal, fecal, and environmental swabs; tissue; milk; hair follicles; semen; ear notches; ear punches; environmental samples; and BioMed Diagnostics InPouch™ TF (Tritrichomonas foetus) culture	Bovine blood, bovine hair, bovine blood cards, bovine ear punches, bovine raw semen, bovine ear supernatant, bovine semen, canine buccal swabs
Run time on instrument*	27 minutes	25 minutes
Applications	Real-time PCR, RT-PCR, and sequencing	Real-time PCR, RT-PCR, and sequencing
Target analyte	Viral RNA/DNA and bacterial DNA	Genomic DNA
Number of washes	2	3
Shipping conditions	Shipped at ambient temperature	Shipped at ambient temperature
Supported Instruments	KingFisher Flex instrument, KingFisher Duo Prime instrument, KingFisher mL instrument, MagMAX Express-96 magnetic head, KingFisher Apex instrument with 96 deep-well head*	KingFisher Flex, KingFisher Apex, Kingfisher Presto

*Other options may vary

MagMAX CORE modules

Some challenging targets or sample types may require additional components not included in the MagMAX CORE Nucleic Acid Purification Kit. So we offer flexible modules that are used in conjunction with the “core” chemistry. This allows you to easily add new applications without needing to introduce new chemistries.

	MagMAX CORE Mastitis & PanBacteria Module + MagMAX CORE Nucleic Acid Purification Kit	MagMAX CORE Mechanical Lysis Module	MagMAX CORE Disruption Module
Overview	Comprehensive module that aids in the processing of bacteria, especially those associated with mastitis in cattle. This kit includes an optimized lysis solution and an adjusted extraction procedure to include nucleic acid recovery from all bacteria, including gram positive strains.	A supplement to the MagMAX CORE Nucleic Acid Purification Kit, designed to process hard-to-lyse organisms such as Mycobacterium avium paratuberculosis (MAP) and bovine tuberculosis in feces, milk, and environmental samples.	The MagMAX CORE Disruption Module is designed to provide efficient mechanical lysis for tough sample types like Mycobacterium avium paratuberculosis (MAP), enhancing nucleic acid extraction processes. It is compatible with our sample extraction kits and helps ensure high-quality DNA and RNA yield.
Catalog numbers	A40289	A32836	A40004818 (1 module)
Throughput/reactions	Up to 96 reactions per run	Varies by kit; typically, high throughput, up to 96 reactions per run	500 reactions
Supported samples	Milk, swabs, and other biological samples	Tissue, bacterial cultures, and other challenging samples DNA (genomic), DNA/RNA (pathogen), total nucleic acids, DNA/RNA (viral)	They aid in the processing of hard-to-lyse organisms like Mycobacterium avium paratuberculosis (MAP).
Cycling mode/run time	Heated: 50 minutes	Heated: 35–50 minutes, depending on the sample type	Approximately 45 minutes per run
Applications	Suitable for fresh, frozen, or preserved milk samples, including those with high somatic cell counts Bacterial pathogen identification in veterinary samples	Real-time PCR, RT-PCR Nucleic acid extraction from difficult samples, including tissue and bacterial cultures	Nucleic acid purification for downstream applications such as PCR, qPCR, and sequencing
Target analyte	Bacterial DNA	Bacteria, blood, DNA, liquid samples (e.g., serum), other samples, RNA, tissue, viral samples	Genomic DNA / RNA
Number of washes	3	3-4 washes, depending on specific kit	2
Shipping conditions	Shipped at ambient temperature	Shipped at ambient temperature	Shipped at ambient temperature
Supported Instruments	KingFisher Flex, KingFisher Duo Prime	KingFisher Flex, KingFisher Duo Prime	KingFisher Flex, KingFisher Duo Prime

We also sell and support additional kits that are widely used with proven histories that have validated workflows for major viral RNA and targets.

Performance data

Accelerate

The MagMAX CORE Nucleic Acid Purification Kit helps improve lab efficiency. Various studies were run to demonstrate the quality of data and reduction of sample processing time using the MagMAX CORE Kit and MagMAX CORE Mastitis & Panbacteria Module.

See performance of the MagMAX CORE Nucleic Acid Extraction Kit

Or contact a product specialist to request more detailed performance data.