Dionex Inuvion Core IC System: Simple, intuitive ion analysis

Perform reliable, basic ion analysis while maintaining low operating costs with the Thermo Scientific Dionex Inuvion Core IC System. This instrument provides all the benefits of chemical suppression and high-pressure operation, with the ability to upgrade features to perform additional applications as your needs and budget allow. Built on the latest innovative technology, the Dionex Inuvion Core IC System is designed to maximize productivity and uptime, so you can be sure your ion analyses are producing high-quality, reliable results.


Flexible, upgradeable system

As a part of the Dionex Inuvion platform, this instrument can be easily upgraded from the Dionex Inuvion Core to the Dionex Inuvion (with or without Reagent-Free IC capabilities) as your analysis needs change. User-installable accessories can be swapped in and out of the instrument in minutes for extended application capabilities.

Maximum productivity and performance

The Dionex Inuvion Core IC System is built with state-of-the-art pump technology and electronics for improved day-to-day reliability. System self-diagnostics also detect issues with hardware and consumables, giving you the confidence that it will be ready to run whenever you are.

Simple user experience

The smart, function-driven engineering of this ion chromatography system allows users to quickly and easily access all necessary components, connections and consumables without a stepstool or extra tools.

Fast and easy setup

With automated startup and shutdown routines, the Dionex Inuvion Core IC System is quickly ready to run samples with minimal delay or user intervention. Simple how-to videos built into the software reduce training time and simplify overall setup and operation.

High-pressure operation

The Dionex Inuvion Core IC System can operate at pressures up to 5,000 psi. This pressure allows the instrument to support a full range of high-performance 4 µm-particle-size Thermo Scientific Dionex IC columns for improved speed and quality of results.

Chromatography data system

The Dionex Inuvion Core IC System comes with the easy-to-use Thermo Scientific Chromeleon Chromatography Data System (CDS). This CDS platform automates and optimizes daily tasks and helps even inexperienced users achieve consistent, high-quality results.


System specifications

The table below provides an overview of the Dionex Inuvion Core IC System specifications. Not all specifications are listed. For a full list of the specifications, download the Dionex Inuvion Core IC System specifications sheet.


Dionex Inuvion Core IC System

Analytical pump and fluidics


Serial dual-reciprocating pistons, microprocessor-controlled constant stroke, variable speed


Chemically inert, metal-free PEEK pump heads and flow paths compatible with aqueous eluents of pH 0–14 and reversed-phase solvents

Pump operating pressure

0–35 MPa (0–5000 psi)

Flow rate range

0.00–5.00 mL/min in 0.01 mL/min increments

Flow precision

<0.1%, typically

Flow accuracy

<0.1%, typically

Pressure ripple


Eluent on-off valve


Leak sensor

Optical, standard

Piston seal wash (optional)

Pump head wash can be operated in continuous or intermittent mode when connected to rinse solution supply

Pressure alarm limits

Upper and lower limit pressure alarms can be set

Eluent bottles

Standard 2 L polypropylene bottle; allows various sizes

Eluent bottle pressure regulator (optional)

Supported by digital controlled regulator with display

Injection valve

6-port, 2-position Rheodyne valve, electronically activated

Columns supported

2, 3, 4, and 5 mm ID; maximum length 250 mm analytical column with 50 mm guard column

Column heater (optional)

Operating temperature range

10 to 60 °C (50 to 140 °F); settable within the software; minimum working range is 5 °C above ambient temperature

Temperature accuracy

±0.5 °C at sensor, at calibration points (35, 45 °C)

Suppressors and control

Chemical suppression

2 mm and 4 mm anion and cation suppressor types

Carbonic acid removal for anions

Thermo Scientific Dionex CRD 200 Carbonate Removal Device for use with hydroxide eluents or Dionex CRD 300 for use with carbonate eluents

Non-suppressed chromatography

Yes, supported

Suppressor wear parts

Optional regenerant pump for chemical suppressor

Dynamic suppression capacity


  • Thermo Scientific Dionex ACRS 500 (4 mm): 150 μeq/min
  • Thermo Scientific Dionex ACRS 500 (2 mm): 75 μeq/min


  • Thermo Scientific Dionex CCRS 500 (4 mm): 75 μeq/min
  • Thermo Scientific Dionex CCRS 500 (2 mm): 37.5 μeq/min

Void volumes

  • <50 μL for 4mm Thermo Scientific Dionex CRS 500 suppressors
  • <15 μL for 2mm Dionex CRS 500 suppressors

Conductivity detector electronics and flow cell


Microprocessor-controlled digital signal processor

Cell drive

128 kHz square wave




0.002 nS/cm

Full-scale output ranges

Digital input signal range 0-18,000 μS/cm, with auto-ranging; analog output signal range 0-18,000 μS/cm

Temperature compensation

Variable, default set at 1.7%/°C at cell temperature

Temperature range

Ambient +7 °C, 30 to 60 °C

Cell electrodes

Passivated 316 stainless steel; compatible with MSA

Cell body

Chemically inert polymeric material

Cell volume

<1 µL

Heat exchanger

Inert, tortuous path for low axial dispersion

Maximum cell operating pressure

10 MPa (1,500 psi)

Data filter

Rise times from 0 to 10 s, Data Collection Rate 1 to 100 Hz, user selectable


Automation using autosampler

For more information about available autosamplers, visit IC Autosamplers

System software


Chromeleon CDS, requires Microsoft® Windows® 10 or 11

Physical specifications

Dimensions (h × w × d)

66.1 x 29.2 x 43.2 cm (26.0 x 11.5 x 17.0 in.)


15.3 kg (33.7 lb)

Power requirements

100–240 V AC, 50–60 Hz autoranging

Operating temperature

4–40 °C (40–104 °F)

Operating humidity range

20-80% relative, non-condensing

Control modes

Full control through Chromeleon CDS software; alternative control through TTL or relay closures; one relay output, two TTL outputs, two assignable TTL inputs

USB communication protocol

One USB input; three USB outputs

Ordering information


Optional accessories