Single-Use Bioprocessing Equipment and Automation

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Reimagine efficiency and innovation with single-use solutions

Whether you're advancing your biopharmaceutical manufacturing capabilities or seeking to optimize existing processes, Thermo Scientific single-use bioprocessing equipment and automation solutions enable exceptional performance, reliability, and quality.

 

Designed and manufactured for easy integration and customization across upstream and downstream bioprocessing workflows, our bioprocessing equipment offers ergonomic, scalable solutions that prioritize quality, flexibility, and efficiency with speed-to-market, sustainability, and risk mitigation as top priorities. 


Featured bioprocessing equipment and automation solutions

Single-Use Bioreactor Systems

The Thermo Scientific Bioreactor portfolio offers versatility and innovative design, with streamlined options for a range of bioprocessing applications.

 

Single-Use Mixers

Designed for a range of upstream and downstream applications—from media and buffer preparation to viral inactivation to cell re-suspension.

 

Single-Use Fermentor System

Designed to meet the high demands of industrial microbiology with efficient mass transfer, mixing, and temperature control.

 

DynaChrom Single-Use Chromatography System

Facilitates precise separation while helping alleviate the burden of complex and costly systems and permits configurability to support your growing needs.
 

DynaSpin Single-Use Centrifuge


Offers a robust single-use harvest solution that helps deliver excellent separation and next-generation automation, contributing to the success of your drug manufacturing workflow.

Automation Software and Controllers


Thermo Scientific software powered by Delta V and controllers contributes to data transferability and scalability with the capacity to control systems, from research to commercial manufacturing.

Experience the innovation of DynaDrive S.U.B. now available at 5 L for process development.

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Key features and benefits of Thermo Scientific bioprocessing equipment and automation

Our controllers and hardware run on Emerson DeltaV data management solutions, allowing for flexibility in operating systems with the integration of modular hardware, novel single-use sensors, and advanced bioreactors for strategic and streamlined bioprocess control.

  • Automated systems: Our TruBio Software with G3 Controllers enable precise automation and monitoring, enhancing production efficiency and minimizing risk
  • High-quality consumables: BioProcess Containers (BPCs) with BioTitan Retention Devices are designed to help minimize risk, enhance reliability, and enable product purity while helping you reach you sustainability goals
  • Sustainable solutions and resource efficiency: Low water and energy consumption contribute to cost savings and reduced environmental footprint over time
  • Quick facility builds with low capital expenditure: Accelerate facility design and commissioning while reducing upfront costs with modular and flexible single-use systems that defer major capital investment and ensure faster time-to-market maximizing resource utilization

Learn more about Sustainable Film

Interested in leasing or financing our equipment? Manage your resources by taking advantage of financing and leasing options from Thermo Fisher Scientific.

Bioprocess services and support

Single-Use FlexCare Services

This full range of service solutions, supported by dedicated service engineers, are designed to help protect your processes against unforeseen downtime, help ensure productivity, improve operational costs, and help enable your facility to function at a maximum operational capacity.

Bioprocessing equipment and automation resources

Brochure

Thermo Scientific's lab bioreactor systems enable precise, automated, and scalable control of cell culture and fermentation processes.

Brochure

Redefine your bioprocessing with a wide variety of single-use mixers.

Whitepaper

Single-use vs. stainless steel—The biopharmaceutical manufacturing debate

Explore BioProcess Insights


The Bioprocess Insights Hub by Thermo Fisher Scientific is designed for biomanufacturing professionals, offering educational resources to optimize single-use bioprocessing workflows. It features articles, guides, and case studies on topics such as assembly design, contamination mitigation, and technology transfer. Resources include application notes, brochures, white papers, videos, and webinars, covering areas like process optimization, scalability, quality, and sustainability.

Bioprocessing equipment and automation 3D product tours

DynaChrom Single-Use Chromatography System

DynaDrive Single-Use Bioreactor

DynaSpin Single-Use Centrifuge

HyPerforma Single-Use Bioreactor


Frequently asked questions

Single-use technology is used at every step from media and buffer preparation through final purification. Single-use mixers use disposable bags, liners, or rigid containers and can be used for liquid/liquid and liquid powder mixing. Cells that produce biologics are grown in single-use bioreactors. Downstream concentration and purification steps are performed with single-use centrifugation (e.g. DynaSpin Single-Use Centrifuge) and chromatography (DynaChrom Single-Use Chromatography System).

Unlike re-usable systems that are often open at different points in the workflow, many single-use systems use closed tubing (fluid management systems) to transport bioprocessing fluids from one step in the workflow to the next, significantly reducing contamination risk.

Like most single-use bioprocessing equipment, The DynaSpin Single-Use Centrifuge has disposable components. It uses a unique single-use Magnetic Rotor and pump design to maintain a closed, automated, single-use system.

Single-use chromatography systems like the DynaChrom Single-Use Chromatography System deliver bioprocessing fluids to the column using single-use fluid transfer assemblies. Single-use filters and pre-columns can be integrated into the systems for better efficiency.

By definition, single-use equipment has disposable components. The environmental impacts of these are often less than the impact of cleaning solutions, water and electricity required to properly clean re-usable equipment between runs. Some equipment such as the DynaSpin Single-Use Centrifuge replace steps using other disposable equipment like filters. 

Systems are available for as little as  1 L up to about 5,000 L. The modular design of single-use equipment saves space reducing the need for buildouts. Equipment can be multiplexed to achieve larger volumes.

Factors to consider include integration capabilities, process control, regulatory compliance, scalability, and ease of use. For example, Thermo Scientific TruBio Bioprocess Control Software is powered on the DeltaV Distributed Control Platform from Emerson, widely known for integration, validated for GMP, 21 CFR Part 11 compliant, and requires no programming or scripting.

For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.