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Single-step purification of many antibody formats
CaptureSelect™ Antibody Toolbox products are designed to enhance the success of your antibody purification processes. The products offer specific advantages over purification using Proteins A, G, and L, including unique target specificity and simplified elution protocols. Each product has defined target specificity for distinct antibody types and regions, minimizing the need for you to test multiple media products to determine the optimal choice. Learn more about these products or view our latest publication Pure Potential on IPT.
CaptureSelect™ Antibody Toolbox resins for biomolecule purification
| IgG, all subclasses | Characteristics |
| CaptureSelect™ IgG-CH1 (resin) | Suitable for purification of human IgG and all Fab fragments |
| CaptureSelect™ IgG-CH1 (pre-packed column) | Suitable for purification of human IgG and all Fab fragments |
| CaptureSelect™ FcXL | Specific for human IgG, recognizing all four subclasses, offering mild elution conditions |
| CaptureSelect™ IgG-Fc (Hu) | Specific for human IgG, recognizing all four subclasses |
| CaptureSelect™ IgG-Fc (ms) | Designed to purify IgG from multiple species by high-affinity binding to the Fc region of IgGs |
| Light chains | Characteristics |
| CaptureSelect™ KappaXL | To purify all human kappa Ig light chain–containing products, offering mild elution conditions |
| CaptureSelect™ LC-kappa (Hu) | To purify all human kappa Ig light chain–containing products |
| CaptureSelect™ LC-kappa (mur) | Murine Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments, and poly Ig from mouse, rat, and guinea pig |
| CaptureSelect™ LC-lambda (Hu) | To purify all human lambda Ig light chain–containing products |
| CaptureSelect™ LC-lambda (ung) | Suitable for Ig, Fab fragments and free light chains from ungulates (bovine, horse, donkey, sheep, goat, pig) |
| CaptureSelect™ LC-lambda (mouse) | Mouse Ig binder recognizing IgG, IgM, IgA, IgD, IgE, and Fab fragments containing a lambda light chain from mouse |
| CaptureSelect™ LC-lambda (rat) | Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments containing a lambda light chain from rat or guinea pig |
| Isotype-specific | Characteristics |
| CaptureSelect™ IgM | IgM resin suitable for human, mouse, and rat IgMs |
| CaptureSelect™ IgA | For purification of human IgA, IgA dimers, and secretory IgA (sIgA) |
| CaptureSelect™ IgA-CH1 (Hu) | For purification of human IgA, IgA dimers, and secretory IgA (sIgA) and Fab fragments thereof |
| IgG subclass–specific | Characteristics |
| CaptureSelect™ IgG4 (Hu) | Specific for human IgG4 without any cross-binding to other subclasses or species |
| CaptureSelect™ IgG1 (Hu) | Specific for human IgG1 without any cross-binding to other subclasses or species |
| CaptureSelect™ IgG3 (Hu) | Specific for human IgG3 without any cross-binding to other subclasses or species |
| IgG, all subclasses | Characteristics |
| CaptureSelect™ IgG-CH1 (resin) | Suitable for purification of human IgG and all Fab fragments |
| CaptureSelect™ IgG-CH1 (pre-packed column) | Suitable for purification of human IgG and all Fab fragments |
| CaptureSelect™ FcXL | Specific for human IgG, recognizing all four subclasses, offering mild elution conditions |
| CaptureSelect™ IgG-Fc (Hu) | Specific for human IgG, recognizing all four subclasses |
| CaptureSelect™ IgG-Fc (ms) | Designed to purify IgG from multiple species by high-affinity binding to the Fc region of IgGs |
| Light chains | Characteristics |
| CaptureSelect™ KappaXL | To purify all human kappa Ig light chain–containing products, offering mild elution conditions |
| CaptureSelect™ LC-kappa (Hu) | To purify all human kappa Ig light chain–containing products |
| CaptureSelect™ LC-kappa (mur) | Murine Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments, and poly Ig from mouse, rat, and guinea pig |
| CaptureSelect™ LC-lambda (Hu) | To purify all human lambda Ig light chain–containing products |
| CaptureSelect™ LC-lambda (ung) | Suitable for Ig, Fab fragments and free light chains from ungulates (bovine, horse, donkey, sheep, goat, pig) |
| CaptureSelect™ LC-lambda (mouse) | Mouse Ig binder recognizing IgG, IgM, IgA, IgD, IgE, and Fab fragments containing a lambda light chain from mouse |
| CaptureSelect™ LC-lambda (rat) | Ig binder recognizing IgG, IgM, IgA, IgD, IgE, Fab fragments containing a lambda light chain from rat or guinea pig |
| Isotype-specific | Characteristics |
| CaptureSelect™ IgM | IgM resin suitable for human, mouse, and rat IgMs |
| CaptureSelect™ IgA | For purification of human IgA, IgA dimers, and secretory IgA (sIgA) |
| CaptureSelect™ IgA-CH1 (Hu) | For purification of human IgA, IgA dimers, and secretory IgA (sIgA) and Fab fragments thereof |
| IgG subclass–specific | Characteristics |
| CaptureSelect™ IgG4 (Hu) | Specific for human IgG4 without any cross-binding to other subclasses or species |
| CaptureSelect™ IgG1 (Hu) | Specific for human IgG1 without any cross-binding to other subclasses or species |
| CaptureSelect™ IgG3 (Hu) | Specific for human IgG3 without any cross-binding to other subclasses or species |
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