Next-generation sequencing, demystified
Solving complex biological questions using next-generation sequencing (NGS) shouldn’t require magical powers. You just want to know what variants are present so you can focus on the biological implications of that change.
Ion Torrent™ products offer rapid, simple, and cost-effective NGS solutions, to help you find meaningful variants in your research and understand their potential implications. You’ll stay focused on your project and avoid the bottlenecks of data analysis. Maybe there’s a little magic to it after all.
Do you need to understand the molecular mechanisms of gene transcription and regulation in your disease research?
We can help you obtain gene level expression for RefSeq transcripts from as little as 10 ng FFPE RNA, design a custom panel to profile a select set of transcripts, detect the gene fusions in lung FFPE samples, and identify known and novel transcripts including gene fusions and alternatively spliced isoforms.
The Ion Proton™ System helps reduce the high cost and complexity of high-throughput sequencing, making it more available to your lab for your specific research needs. The system has been designed with affordability in mind. Combining semiconductor sequencing technology with biochemistry to directly translate chemical information into digital data minimizes the need for expensive optics and complex sequencing chemistries, resulting in a sequencing system that is highly-affordable to own and operate.
Do you need to overcome the bottlenecks of NGS data analysis and find the biological meaning of your variants quickly and easily?
Ion Reporter™ Software helps you find the biological meaning of your research data quickly and easily. The software provides an optimized suite of simple data analysis tools that streamline Ion PGM™ and Ion Proton™ System data analysis, to enable easy data analysis across a variety of research applications and fast results with automated workflows. Secure your data using controlled access with role-based logins, locked workflows, and audit logs to help maintain a traceable and secure environment. Analyze and share data in the cloud, or analyze and store data on-site with the local Ion Reporter™ Server System.
Do you need to compare non-human species to understand the genetic diversity within your samples?
We can help you design a targeted gene panel for microbial or model organisms, implement genotyping by sequencing for AgBio trait mapping, and analyze small whole genomes in de novo and comparative genomics.
The Ion Chef™ System simplifies the workflow for Ion PGM™ and Ion Proton™ systems, providing an automated, high-throughput research solution for reproducible template preparation and chip loading. The system enables reproducible chip loading for users of any experience level and provides sample and reagent tracking with an onboard tracking system. Increase your lab's productivity with the typical setup-time of just 15 minutes and the ability to perform overnight runs.
With the Ion Torrent™ Personal Genome Machine (PGM™) System, human disease researchers can detect variants by targeted gene sequencing in cancer and genetic disorders, and microbiologists can easily type a bacteria or virus, or characterize novel microbes. Now, more laboratories can adopt powerful next-generation sequencing technology to get answers faster —with a system that enables increased throughput, higher accuracy, and the simplest workflow from sample preparation through to data analysis.