No need to worry about your trace level analysis anymore – find the right tools to detect down to the last femtogram!
Trace analysis requires many different techniques to reach required detection limits. It all starts with the right sample preparation and using the best quality vials to prevent the loss of analytes before they enter the LC-MS and/or GC-MS.
We offer solutions and expertise.
Forensic and toxicology analysis has continuously changing requirements.
Everything leaves a trace!
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In the spotlight: Fentanyl/norfentanyl analysis
From sample to results - the toxicology and forensic lab workflow
Improving analytical results often means focusing mainly on analytical instruments and method parameters. But do you ask yourself the important questions?
- Am I using the right material in my SPE for either LC-MS or GC-MS analysis?
- Am I using the best possible glass quality for my vials and GC liners?
- Do my samples require storage and/or filtration?
We are a global leader for chromatography consumables and offer you a wide portfolio of best in class vials and SPE cartridges, as well as syringes and syringe filters.
Resources
On Demand Webinars
- Fundamentals of Solid Phase Extraction for forensics and toxicology: Hear about the theory and concept of solid phase extraction, sample preparation options, step-by-step guide and toubleshooting.
- A workflow for the analysis of new psychoactive substances:
A complete workflow for NPS from sample preparation, through all relevant steps to detection wtih single quadrupole GC-MS is presented.
Request instant access ›
Video
- Workflow for the analysis of new psychoactive substances at LVR:
This video shows a complete workflow for the analysis of drugs of abuse including SPE and GC-MS.
Request instant access ›
eBook
- Clinical research and forensic handbook:
Free 880 pages handbook with technical notes, educational tools, peer reviewed references and new information about our innovative sample preparation, chromatography and MS solutions — to help facilitate your clinical research and forensic testing.
Request instant access ›
White Paper
Forensic/toxicology analyses can be complex, and can require the use of multiple techniques to obtain accurate results. LC-MS is especially helpful when looking into polar analytes and structural changes in the world of drugs of abuse. To obtain the necessary tools and knowledge required for success in this challenging field, we offer webinars, online workflows and solutions, educational videos, and the opportunity to talk to one of our experts.
Resources
On-Demand Webinars
- Addressing Challenges with Confidence using LC-MS for Clinical Research
Request instant access › - Use of LC-MS/MS for Testing of Nicotine in e-Cigarette Vapors | Broughton Nicotine Services
Request instant access ›
- High Resolution Orbitrap MS for Detecting New Psychoactive Drugs: A User’s Perspective
- Advances in Forensic Analysis - When to Use HRAM/HRMS
- An Intelligence-Led Approach to the Detection of Drugs of Abuse and Novel Psychoactive Substances
Videos
- Reducing Caseload in Forensic Laboratories (6 minutes)
- Orbitrap Mass Spectrometry-New Tools to Combat the Growing Opioid Epidemic
Technical Notes
Forensic Toxicology Learning Center
- Whether you screen and confirm known compounds, identify unknowns or advance forensic research, we have a solution to meet your current and future needs.
Access the forensic toxicology library/Learning Center ›
eBooks
- Removing Doubt in Forensic Science – Mass Spectrometry Workflows Solving Forensic Cases:
Overview of the current state of forensic chemistry and the latest mass spectrometry technology for staying ahead of your casework
Request instant access › - Identify Rapidly Evolving Novel Psychoactive Drug Substances Faster;
Discover the growing list of NPS, identifying and prohibiting NPS faster, reducing human and societal cost, determining drug circulation networks more rapidly, and staying ahead of emerging trends.
Request instant access › - Tomorrow’s Quantitation Interactive:
Whether you perform your quantitation analyses by triple quadrupole mass spectrometry or using the high resolution accrate mass (HRAM) capabilities of an Orbitrap system, this compendium gives examples of how to develop robust assays across a variety of different sample types.
Request instant access › - Clinical Research and Forensic Handbook:
Free 880 pages handbook with technical notes, educational tools, peer reviewed references and new information about our innovative sample preparation, chromatography and MS solutions
Request instant access › - Drugs of Abuse: Reliable Analysis through Orbitrap Mass Spectrometry
View now › - Promises and Pitfalls of Alternative Matrices: Capture the Drug Traces You Need
View now ›
Forensic/toxicology is a challenging field, and many analyses that are required are not considered routine. Samples and analytes are subject to change on a daily basis, but GC-MS technology is still the “gold standard” for many unknown analyses. For some analysis, a GC single quadrupole with deconvolution software is ideal. However, there are also more advanced cases which require additional capabilities.
Resources
On-Demand Webinars
- Advances in forensic analysis: When to use GC-MS & GC-MS/MS (23 minutes)
- Advances in forensic analysis. When to Use HRAM/HRMS (22 minutes)
- Reducing caseload in forensic laboratories (6 minutes)
- Effective sample preparation for sensitive analysis of drugs of abuse with GC-MS for clinical research and forensic toxicology (Language: German; 10 minutes)
- Advances in forensic analyses. When to use GC-MS & GC-MS/MS
Videos
- Advances in forensic analyses. When to use GC-MS & GC-MS/MS (23 minutes)
- When to Use HRAM/HRMS (22 minutes)
- Reducing caseload in forensic laboratories (6& minutes)
- Effective sample preparation for sensitive analysis of drugs of abuse with GC-MS for clinical research and forensic toxicology (Language: German; 10 minutes)
Ebook
- Clinical research and forensic handbook:
Free 880 pages handbook with technical notes, educational tools, peer reviewed references and new information about our innovative sample preparation, chromatography and MS solutions
Request instant access ›
Blogs
Technical Notes
From blood alcohol, to drugs of abuse or sports doping analysis – Learn about our innovative forensic applications for your lab. We provide standard solutions to out of the box analytical concepts.
One of the major challenges in the analysis of drugs of abuse is to determine the country and source of origin.
By studying the isotope fingerprints, carbon, nitrogen, hydrogen, oxygen and sulfur, the isotope hunters among other forensic investigations, can reveal the real origin and real geographical cultivation areas of drug of abuse.
Applying isotope fingerprints to forensic questions allows investigators to provide a unique characterization of the sample material and so trace reactants, chemical pathways and reaction conditions, relative to natural processes. From this basis, using isotope fingerprints makes it possible to determine similarities between different drug seizures and authentic material and to follow trafficking routes to their original source.
Resources
Webinar
Video
Whiteboard video on Isotope Fingerprints for forensic applications (including origin of drugs)
View now ›
Blog
How Isotope Hunters Are Using Isotope Fingerprints to Solve Criminal Forensic Cases
Technical notes
Infographic
Immunoassay screening with Thermo Scientific DRI Fentanyl Assay
The DRI Fentanyl Assay is supplied as liquid ready-to-use homogeneous enzyme
immunoassay. The assay uses fentanyl specific monoclonal antibody that can detect fentanyl
without any significant cross-reactivity to other opiate compounds.
Learn more about immunoassay screening for fentanyl detection
Trace elemental analysis
Trace elemental analysis is a key part of analytical science. Whether you are monitoring toxic metals such as arsenic, beryllium, cadmium, chromium, lead and mercury or confirming that pharmaceuticals are free from elemental impurities, getting accurate results is vital.
With our trace elemental analysis portfolio, we have all your elemental analysis requirements covered.
Application and technical notes
Arsenic speciation in human urine by hyphenated ion chromatography (IC) and inductively coupled plasma mass spectrometry (ICP-MS)
Fast and accurate determination of essential and toxic elements in whole blood using ICP-MS for clinical research
ICP-MS as a tool in elemental brain imaging
Advanced ICP-MS techniques for overcoming interferences in LA-ICP-MS bioimaging
Compendium
Improving analytical results often means focusing mainly on analytical instruments and method parameters. But do you ask yourself the important questions?
- Am I using the right material in my SPE for either LC-MS or GC-MS analysis?
- Am I using the best possible glass quality for my vials and GC liners?
- Do my samples require storage and/or filtration?
We are a global leader for chromatography consumables and offer you a wide portfolio of best in class vials and SPE cartridges, as well as syringes and syringe filters.
Resources
On Demand Webinars
- Fundamentals of Solid Phase Extraction for forensics and toxicology: Hear about the theory and concept of solid phase extraction, sample preparation options, step-by-step guide and toubleshooting.
- A workflow for the analysis of new psychoactive substances:
A complete workflow for NPS from sample preparation, through all relevant steps to detection wtih single quadrupole GC-MS is presented.
Request instant access ›
Video
- Workflow for the analysis of new psychoactive substances at LVR:
This video shows a complete workflow for the analysis of drugs of abuse including SPE and GC-MS.
Request instant access ›
eBook
- Clinical research and forensic handbook:
Free 880 pages handbook with technical notes, educational tools, peer reviewed references and new information about our innovative sample preparation, chromatography and MS solutions — to help facilitate your clinical research and forensic testing.
Request instant access ›
White Paper
Forensic/toxicology analyses can be complex, and can require the use of multiple techniques to obtain accurate results. LC-MS is especially helpful when looking into polar analytes and structural changes in the world of drugs of abuse. To obtain the necessary tools and knowledge required for success in this challenging field, we offer webinars, online workflows and solutions, educational videos, and the opportunity to talk to one of our experts.
Resources
On-Demand Webinars
- Addressing Challenges with Confidence using LC-MS for Clinical Research
Request instant access › - Use of LC-MS/MS for Testing of Nicotine in e-Cigarette Vapors | Broughton Nicotine Services
Request instant access ›
- High Resolution Orbitrap MS for Detecting New Psychoactive Drugs: A User’s Perspective
- Advances in Forensic Analysis - When to Use HRAM/HRMS
- An Intelligence-Led Approach to the Detection of Drugs of Abuse and Novel Psychoactive Substances
Videos
- Reducing Caseload in Forensic Laboratories (6 minutes)
- Orbitrap Mass Spectrometry-New Tools to Combat the Growing Opioid Epidemic
Technical Notes
Forensic Toxicology Learning Center
- Whether you screen and confirm known compounds, identify unknowns or advance forensic research, we have a solution to meet your current and future needs.
Access the forensic toxicology library/Learning Center ›
eBooks
- Removing Doubt in Forensic Science – Mass Spectrometry Workflows Solving Forensic Cases:
Overview of the current state of forensic chemistry and the latest mass spectrometry technology for staying ahead of your casework
Request instant access › - Identify Rapidly Evolving Novel Psychoactive Drug Substances Faster;
Discover the growing list of NPS, identifying and prohibiting NPS faster, reducing human and societal cost, determining drug circulation networks more rapidly, and staying ahead of emerging trends.
Request instant access › - Tomorrow’s Quantitation Interactive:
Whether you perform your quantitation analyses by triple quadrupole mass spectrometry or using the high resolution accrate mass (HRAM) capabilities of an Orbitrap system, this compendium gives examples of how to develop robust assays across a variety of different sample types.
Request instant access › - Clinical Research and Forensic Handbook:
Free 880 pages handbook with technical notes, educational tools, peer reviewed references and new information about our innovative sample preparation, chromatography and MS solutions
Request instant access › - Drugs of Abuse: Reliable Analysis through Orbitrap Mass Spectrometry
View now › - Promises and Pitfalls of Alternative Matrices: Capture the Drug Traces You Need
View now ›
Forensic/toxicology is a challenging field, and many analyses that are required are not considered routine. Samples and analytes are subject to change on a daily basis, but GC-MS technology is still the “gold standard” for many unknown analyses. For some analysis, a GC single quadrupole with deconvolution software is ideal. However, there are also more advanced cases which require additional capabilities.
Resources
On-Demand Webinars
- Advances in forensic analysis: When to use GC-MS & GC-MS/MS (23 minutes)
- Advances in forensic analysis. When to Use HRAM/HRMS (22 minutes)
- Reducing caseload in forensic laboratories (6 minutes)
- Effective sample preparation for sensitive analysis of drugs of abuse with GC-MS for clinical research and forensic toxicology (Language: German; 10 minutes)
- Advances in forensic analyses. When to use GC-MS & GC-MS/MS
Videos
- Advances in forensic analyses. When to use GC-MS & GC-MS/MS (23 minutes)
- When to Use HRAM/HRMS (22 minutes)
- Reducing caseload in forensic laboratories (6& minutes)
- Effective sample preparation for sensitive analysis of drugs of abuse with GC-MS for clinical research and forensic toxicology (Language: German; 10 minutes)
Ebook
- Clinical research and forensic handbook:
Free 880 pages handbook with technical notes, educational tools, peer reviewed references and new information about our innovative sample preparation, chromatography and MS solutions
Request instant access ›
Blogs
Technical Notes
From blood alcohol, to drugs of abuse or sports doping analysis – Learn about our innovative forensic applications for your lab. We provide standard solutions to out of the box analytical concepts.
One of the major challenges in the analysis of drugs of abuse is to determine the country and source of origin.
By studying the isotope fingerprints, carbon, nitrogen, hydrogen, oxygen and sulfur, the isotope hunters among other forensic investigations, can reveal the real origin and real geographical cultivation areas of drug of abuse.
Applying isotope fingerprints to forensic questions allows investigators to provide a unique characterization of the sample material and so trace reactants, chemical pathways and reaction conditions, relative to natural processes. From this basis, using isotope fingerprints makes it possible to determine similarities between different drug seizures and authentic material and to follow trafficking routes to their original source.
Resources
Webinar
Video
Whiteboard video on Isotope Fingerprints for forensic applications (including origin of drugs)
View now ›
Blog
How Isotope Hunters Are Using Isotope Fingerprints to Solve Criminal Forensic Cases
Technical notes
Infographic
Immunoassay screening with Thermo Scientific DRI Fentanyl Assay
The DRI Fentanyl Assay is supplied as liquid ready-to-use homogeneous enzyme
immunoassay. The assay uses fentanyl specific monoclonal antibody that can detect fentanyl
without any significant cross-reactivity to other opiate compounds.
Learn more about immunoassay screening for fentanyl detection
Trace elemental analysis
Trace elemental analysis is a key part of analytical science. Whether you are monitoring toxic metals such as arsenic, beryllium, cadmium, chromium, lead and mercury or confirming that pharmaceuticals are free from elemental impurities, getting accurate results is vital.
With our trace elemental analysis portfolio, we have all your elemental analysis requirements covered.
Application and technical notes
Arsenic speciation in human urine by hyphenated ion chromatography (IC) and inductively coupled plasma mass spectrometry (ICP-MS)
Fast and accurate determination of essential and toxic elements in whole blood using ICP-MS for clinical research
ICP-MS as a tool in elemental brain imaging
Advanced ICP-MS techniques for overcoming interferences in LA-ICP-MS bioimaging
Compendium
