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产品信息
A33350
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
1-475
标签
GST-tag
分子量
80.2 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris HCl, pH 7.5, with 25% glycerol, 0.25mM DTT, 0.1mM EDTA, 150mM NaCl, 10mM glutathione, 0.1mM PMSF
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This CDC42 BPG (MRCKG) recombinant human protein (1-475) was expressed in insect cells.
CDC42 BPG (MRCKG) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z'-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
Protein Form: Recombinant, Active, Catalytic
靶标信息
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC42 binding protein kinase gamma (DMPK-like); CDC42-binding protein kinase gamma; CDC42BPG; DMPK-like gamma; MRCK gamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; myotonic dystrophy protein kinase like protein; Myotonic dystrophy protein kinase-like alpha; myotonic dystrophy protein kinase-like gamma; Serine/threonine-protein kinase MRCK gamma
基因别名: CDC42BPG; DMPK2; HSMDPKIN; KAPPA-200; MRCKG; MRCKgamma
UniProt ID: (Human) Q6DT37
Entrez Gene ID: (Human) 55561
