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产品信息
PV6285
产品规格
种属
Human
Expression System
Baculovirus
氨基酸序列
1-795
标签
GST-tag
分子量
84.2 kDa
分类
Recombinant
类型
Protein
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris HCl, pH 7.5, with 150mM NaCl, 0.1mM PMSF, 25% glycerol, 0.1mM EDTA, 0.25mM DTT, 10mM glutathione
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Recombinant full-length human CDK11 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use
Related Product:
LanthaScreen™ Eu Kinase Binding Assay
Protein Form: Recombinant
靶标信息
CDK11 is a member of the cyclin-dependent kinase 11 family which is known to be essential for eukaryotic cell cycle control and it is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. CDK11 is a negative regulator of normal cell cycle progression and Its expression is regulated during murine embryogenesis, and its activity is coordinately regulated with that of p34 (cdc2) during the cell cycle. CDK11 gene may harbor 1 or more tumor suppressor genes that affected by chromosome 1p36 modifications in neuroblastoma. CDK11 could be cleaved by caspases and was demonstrated to play roles in cell apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC-related protein kinase p58; cell division cycle 2-like 1 (PITSLRE proteins); cell division cycle 2-like 2 (PITSLRE proteins); Cell division cycle 2-like protein kinase 1; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Cell division protein kinase 11B; CLK-1; Cyclin-dependent kinase 11A; Cyclin-dependent kinase 11B; Galactosyltransferase-associated protein kinase p58/GTA; p58 CLK-1; PITSLRE B; PITSLRE protein kinase beta; PITSLRE serine/threonine-protein kinase CDC2L1; PITSLRE serine/threonine-protein kinase CDC2L2
基因别名: CDC2L1; CDC2L2; CDC2L3; CDK11; CDK11-p110; CDK11-p46; CDK11-p58; CDK11A; CDK11B; CLK-1; p58; p58CDC2L1; p58CLK-1; p58GTA; PITSLRE; PITSLREA; PITSLREB; PK58
UniProt ID: (Human) Q9UQ88, (Human) P21127
Entrez Gene ID: (Human) 728642, (Human) 984
