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Invitrogen
Human COPS4 (aa 318-406) Control Fragment Recombinant Protein
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产品信息
RP-104761
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
NITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHFETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83634. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COP9 constitutive photomorphogenic homolog subunit 4; COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) isoform COPS4_1; COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) isoform COPS4_2; COP9 constitutive photomorphogenic-like protein subunit 4; COP9 signalosome complex subunit 4; JAB1-containing signalosome subunit 4; SGN4; signalosome subunit 4; testis tissue sperm-binding protein Li 42a; unnamed protein product
基因别名: COPS4; CSN4; SGN4
UniProt ID: (Human) Q9BT78
Entrez Gene ID: (Human) 51138
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