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Invitrogen
Human CTRL (aa 128-212) Control Fragment Recombinant Protein
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产品信息
RP-95843
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
ASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAGGAGASSCQG
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56959. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The CTRL gene encodes chymotrypsin-like protein, a serine protease involved in the digestion of proteins by cleaving peptide bonds. It belongs to the chymotrypsin family of enzymes that are predominantly expressed in the pancreas and play crucial roles in the breakdown of dietary proteins in the small intestine. CTRL functions by hydrolyzing specific peptide bonds, contributing to efficient protein digestion and nutrient absorption. This enzyme's activity is tightly regulated to prevent premature activation within the pancreas, which could lead to pancreatitis or other digestive disorders. The study of the CTRL gene is significant in understanding the mechanisms of digestive health and in diagnosing pancreatic disorders. Furthermore, CTRL's enzyme activity and its role in proteolytic pathways make it an important target for research in digestive enzyme supplementation therapies and treatment strategies for conditions involving impaired protein digestion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chymotrypsin-like; Chymotrypsin-like protease CTRL-1
基因别名: CTRL; CTRL1
UniProt ID: (Human) P40313
Entrez Gene ID: (Human) 1506
