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Invitrogen
Human DIO2 (aa 50-123) Control Fragment Recombinant Protein
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产品信息
RP-106163
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
EWRRMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERP
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65489. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5DII; deiodinase-2; deiodonase-2; DIOII; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; Type 2 DI; type 2 iodothyronine deiodinase; Type II iodothyronine deiodinase; Type-II 5'-deiodinase; type-II 5'deiodinase
基因别名: 5DII; D2; DIO2; DIOII; ITDI2; SelY; TXDI2
UniProt ID: (Human) Q92813
Entrez Gene ID: (Human) 1734
