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Invitrogen
Human GABRG1 (aa 19-68) Control Fragment Recombinant Protein
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产品信息
RP-96574
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
RGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQIL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57340. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GABAAR gamma1; GABAAR subunit gamma-1; Gabeg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; Gamma-aminobutyric acid receptor subunit gamma-1
基因别名: GABRG1
UniProt ID: (Human) Q8N1C3
Entrez Gene ID: (Human) 2565
