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This peptide corresponds to 16 amino acids near the amino terminus of human GDF1.
PEP-1515 can be used as a blocking peptide with polyclonal antibody PA5-34473.
Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Embryonic growth/differentiation factor 1; GDF-1
基因别名: DORV; DTGA3; GDF1; RAI
UniProt ID: (Human) P27539
Entrez Gene ID: (Human) 2657