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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62981. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Charged multivesicular body protein 8; CHMP8; hIST1; increased sodium tolerance 1 homolog; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; MGC117220; overexpressed in lung cancer 1; pm28; Putative MAPK-activating protein PM28
基因别名: IST1; KIAA0174; OLC1
UniProt ID: (Human) P53990
Entrez Gene ID: (Human) 9798