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产品信息
RP-10908
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Human Insulin is a two chain, non-glycosylated polypeptide containing 51 amino acids.
分子量
5.8 kDa
分类
Recombinant
类型
Protein
活性
Fully biologically active as compared to WHO reference standard at 28 U/mg.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
purified
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
This is a recombinant protein suitable for use as a control in ELISA and Western blot applications.
Lyophilized Insulin is stable at room temperature for 3 weeks. Reconstitute in sterile 0.005N HCl to a concentration of no more than 1mg/mL. Store lyophilized product at -20°C. Upon reconstitution, store at 4°C for 2-7 days or aliquot and store at -20°C. For long term storage add either HSA or BSA to 0.1%. Avoid repeated freeze-thaw cycles.
靶标信息
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ins; Insulin; preproinsulin; proinsulin
基因别名: IDDM; IDDM1; IDDM2; ILPR; INS; IRDN; MODY10
UniProt ID: (Human) P01308
Entrez Gene ID: (Human) 3630
