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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59182. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-Jun N-terminal kinase protein-associated leucine-zipper protein; c-Jun NH2-terminal kinase-associated leucine zipper protein; cancer/testis antigen 89; human lung cancer oncogene 6 protein; JLP; JNK interacting protein; JNK/SAPK-associated protein; lung cancer oncogene 4; lung cancer oncogene 6; Max-binding protein; mitogen-activated protein kinase 8-interacting protein 4; PIG6; proliferation-inducing gene 6; protein highly expressed in testis; sperm surface protein; sunday driver 1; unnamed protein product
基因别名: CT89; HLC-6; HLC4; HLC6; JIP-4; JIP4; JLP; PHET; PIG6
UniProt ID: (Human) O60271
Entrez Gene ID: (Human) 9043