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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (48%), Rat (48%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53344. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Retroelement silencing factor 1; uncharacterized protein C12orf35
基因别名: C12orf35; KIAA1551; RESF1; UTA2-1
UniProt ID: (Human) Q9HCM1
Entrez Gene ID: (Human) 55196