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Invitrogen
Human LDLRAP1 (aa 153-215) Control Fragment Recombinant Protein
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产品信息
RP-104104
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
MAQAVTLTVAQAFKVAFEFWQVSKEEKEKRDKASQEGGDVLGARQDCTPSLKSLVATGNLLDL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111312. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Autosomal recessive hypercholesterolemia protein; DKFZp586D0624; LDL receptor adaptor protein; Low density lipoprotein receptor adapter protein 1; MGC34705; RP11-70P17.2
基因别名: ARH; ARH1; ARH2; FHCB1; FHCB2; LDLRAP1
UniProt ID: (Human) Q5SW96
Entrez Gene ID: (Human) 26119
