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产品信息
PEP-0611
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Dry ice
产品详细信息
This peptide corresponds to 14 amino acids near the center of human LGI1.
PEP-0611 can be used as a blocking peptide with polyclonal antibody PA5-20491.
靶标信息
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Epitempin 1; Epitempin-1; leucine-rich glioma inactivated 1; Leucine-rich glioma-inactivated protein 1; leucine-rich, glioma inactivated 1; OTTHUMP00000020121; OTTHUMP00000020122
基因别名: ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099; LGI1; UNQ775/PRO1569
UniProt ID: (Human) O95970
Entrez Gene ID: (Human) 9211
