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This peptide corresponds to 14 amino acids near the carboxy terminus of human LRFN2.
PEP-0820 can be used as a blocking peptide with polyclonal antibody PA5-20705.
LRFN2 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: fibronectin type III, immunoglobulin and leucine rich repeat domains 2; Leucine-rich repeat and fibronectin type-III domain-containing protein 2; RP11-535K1.2; Synaptic adhesion-like molecule 1
基因别名: FIGLER2; KIAA1246; LRFN2; SALM1
UniProt ID: (Human) Q9ULH4
Entrez Gene ID: (Human) 57497