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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139890. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2- containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ly6/PLAUR domain-containing protein 1; PHTS; Putative HeLa tumor suppressor; unnamed protein product
基因别名: Lynx2; LYPD1; LYPDC1; PHTS; PSEC0181; UNQ3079/PRO9917
UniProt ID: (Human) Q8N2G4
Entrez Gene ID: (Human) 116372