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产品信息
PEP-0967
产品规格
种属反应
Human
宿主/亚型
Artificial Control
分类
Synthetic
类型
Peptide
偶联物
Unconjugated
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 16 amino acids near the amino terminus of human MARVELD1.
PEP-0967 can be used as a blocking peptide with polyclonal antibody PA5-20853.
靶标信息
MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MARVEL (membrane-associating) domain containing 1; MARVEL domain-containing protein 1; putative MARVEL domain-containing protein 1; RP11-548K23.8
基因别名: bA548K23.8; GB14; MARVD1; MARVELD1; MRVLDC1
UniProt ID: (Human) Q9BSK0
Entrez Gene ID: (Human) 83742
