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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55667. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-protein, skeletal muscle slow isoform; Myosin-binding protein C, slow-type; skeletal muscle C-protein; Slow MyBP-C
基因别名: LCCS4; MYBPC1; MYBPCC; MYBPCS
UniProt ID: (Human) Q00872
Entrez Gene ID: (Human) 4604