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Invitrogen
Human OR10R2 (aa 313-335) Control Fragment Recombinant Protein
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产品信息
RP-101605
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
RNKDVQLAIRKVLGKKGSLKLYN
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111495. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more thana thousandmembers currently predicted to exist.All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Olfactory receptor 10R2; Olfactory receptor OR1-8; olfactory receptor, family 10, subfamily R, member 2
基因别名: OR1-8; OR10R2; OR10R2Q
UniProt ID: (Human) Q8NGX6
Entrez Gene ID: (Human) 343406
