Invitrogen

Human ORMDL1 Synthetic Peptide

Name: Human ORMDL1 Synthetic Peptide
Brand: Invitrogen
SKU: PEP-1260

说明书

技术支持

说明书

技术支持

说明书

技术支持

产品信息

PEP-1260

应用

建议稀释比

已发表文章

中和实验 (Neu)

Assay-dependent

产品规格

种属反应

Human

分类

Synthetic

类型

Peptide

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

purified

保存液

PBS, pH 7.2, with 0.1% BSA

内含物

0.02% sodium azide

保存条件

-20°C

产品详细信息

This peptide corresponds to 16 amino acids near the center of human ORMDL1.

PEP-1260 can be used as a blocking peptide with polyclonal antibody PA5-21146.

靶标信息

The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in -gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.

仅用于科研。不用于诊断过程。未经明确授权不得转售。