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Invitrogen
Human Oncomodulin (aa 1-41) Control Fragment Recombinant Protein
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产品信息
RP-99262
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
MSITDVLSADDIAAALQECRDPDTFEPQKFFQTSGLSKMSA
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Oncomodulin, encoded by the OCM gene located on chromosome 7p22.3, is a protein that belongs to the parvalbumin family of calcium-binding proteins. It is most prominently found in the inner ear, as well as in certain retinal cells and regenerating neurons. Oncomodulin plays a crucial role in calcium ion homeostasis, which is vital for various cellular processes, including signal transduction, cellular motility, and growth. Notably, oncomodulin has been studied for its role in promoting nerve regeneration, particularly within the central nervous system, where it enhances axonal growth and neuronal repair. This makes it a molecule of significant interest for therapeutic strategies aiming to treat nerve injuries or neurodegenerative diseases. Beyond its neuroregenerative potential, oncomodulin is also expressed in some tumor types, which initially led to its association with cancer-related studies. Current research continues to explore its dual roles in both oncology and neurobiology to better understand its functional implications across different tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hCG18255; OM; oncomodulin 1; Oncomodulin-1; Parvalbumin beta
基因别名: OCM; OCM1; OCMN; OM; ONCM
UniProt ID: (Human) P0CE72
Entrez Gene ID: (Human) 654231
