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Invitrogen
Human PAIP2 (aa 2-35) Control Fragment Recombinant Protein
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产品信息
RP-103268
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
KDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYM
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63347. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC72018; PABC1-interacting protein 2; PABP-interacting protein 2; polyA-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2
基因别名: HSPC218; PAIP-2; PAIP2; PAIP2A
UniProt ID: (Human) Q9BPZ3
Entrez Gene ID: (Human) 51247
