Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Human PGPEP1 (aa 113-186) Control Fragment Recombinant Protein
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
RP-95838
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
PESIDSIIDMDAVCKRVTTLGLDVSVTISQDAGRYLCDFTYYTSLYQSHGRSAFVHVPPLGKPYNADQLGRALR
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57245. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Pyroglutamyl-peptidase I (PGPEP1) is a gene located on chromosome 19q13.33, encoding an enzyme involved in the removal of pyroglutamyl residues from the N-terminus of peptides and proteins. This enzymatic activity is fundamental in protein processing and metabolism, ensuring proper protein maturation and degradation. PGPEP1 is expressed in multiple tissues, including the liver and kidney, and plays a role in the regulation of biological processes by modulating the activity and stability of pyroglutamyl-containing bioactive peptides. The enzyme's function is crucial for maintaining cellular homeostasis and can influence physiological pathways such as hormone regulation and immune responses. Dysregulation or mutations in PGPEP1 may impact peptide function and have potential implications for various diseases, although the specific clinical significance is still being researched. Insights into PGPEP1's function are contributing to the understanding of protease-related disorders and therapeutic strategies targeting peptide metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 5-oxoprolyl-peptidase; PAP-I; pGlu-peptidase I; PGP-I; Pyroglutamyl aminopeptidase I; Pyroglutamyl-peptidase 1; Pyroglutamyl-peptidase I; Pyrrolidone-carboxylate peptidase
基因别名: PAP-I; Pcp; PGI; PGP; PGP-I; PGPEP1; PGPI
UniProt ID: (Human) Q9NXJ5
Entrez Gene ID: (Human) 54858
