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Invitrogen
Human PLEKHM2 (aa 545-663) Control Fragment Recombinant Protein
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产品信息
RP-100983
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
GTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSV
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56946. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: novel RUN and PH domain-containing protein; PH domain-containing family M member 2; pleckstrin homology domain containing, family M (with RUN domain) member 2; Pleckstrin homology domain-containing family M member 2; RP11-169K16.1; Salmonella-induced filaments A and kinesin-interacting protein; SifA (Salmonella-induced filaments A) and kinesin-interacting protein; SifA and kinesin-interacting protein
基因别名: KIAA0842; PLEKHM2; SKIP
UniProt ID: (Human) Q8IWE5
Entrez Gene ID: (Human) 23207
