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产品信息
PV3606
产品规格
种属
Human
Expression System
Baculovirus
氨基酸序列
Full length
分子量
67.7 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
20mM HEPES, pH 7.5, with 50% glycerol, 0.05% Triton X-100, 2mM EGTA, 5mM DTT, 2mM EDTA, 250mM NaCl
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Recombinant, Full Length
靶标信息
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.
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生物信息学
蛋白别名: kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; Protein kinase C zeta type; protein kinase C, zeta
基因别名: PKC-ZETA; PKC2; PRKCZ
UniProt ID: (Human) Q05513
Entrez Gene ID: (Human) 5590
