This peptide corresponds to 18 amino acid peptide near the amino terminus of human PTPRD.
PEP-1435 can be used as a blocking peptide with polyclonal antibody PA5-34392.
PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.
蛋白别名: protein tyrosine phosphatase, receptor type, D; protein tyrosine phosphatase, receptor type, delta polypeptide; Protein-tyrosine phosphatase delta; R-PTP-delta; Receptor-type tyrosine-protein phosphatase delta
基因别名: HPTP; HPTPD; HPTPDELTA; PTPD; PTPRD; RPTPDELTA
UniProt ID: (Human) P23468
Entrez Gene ID: (Human) 5789