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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA repair and recombination protein RAD54B; RAD54 homolog B; SNFII/SWIII superfamily member; unnamed protein product
基因别名: RAD54B; RDH54
UniProt ID: (Human) Q9Y620
Entrez Gene ID: (Human) 25788