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Invitrogen
Human RUNX3 (aa 205-221) Synthetic Peptide
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产品信息
PEP-292
产品规格
分类
Synthetic
类型
Peptide
偶联物
形式
Lyophilized
规格
50 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
PEP-292 is a 17 amino acid synthetic peptide whose sequence corresponds to residues 205-221 of human RUNX3. The sequence of this peptide is (amino to carboxyl terminus): T (205) K P F P D R F G D L E R L R M (221)R.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, RUNX3, catalog # PA1-318. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
靶标信息
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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