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产品信息
PEP-1105
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Dry ice
产品详细信息
This peptide corresponds to 17 amino acids near the center of human SCUBE2.
PEP-1105 can be used as a blocking peptide with polyclonal antibody PA5-20991.
靶标信息
SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
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生物信息学
蛋白别名: Protein CEGP1; Scube/You; signal peptide; Signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain, EGF-like 2
基因别名: CEGB1; CEGF1; CEGP1; SCUBE2
UniProt ID: (Human) Q9NQ36
Entrez Gene ID: (Human) 57758
