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Invitrogen
Human SMAGP (aa 60-97) Control Fragment Recombinant Protein
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产品信息
RP-97826
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
YKNKGSYVTYEPTEGEPSAIVQMESDLAKGSEKEEYFI
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58895. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Small cell adhesion glycoprotein (SMAGP) is a gene located on chromosome 1p33 that encodes a transmembrane protein involved in cell adhesion processes. SMAGP is primarily expressed in epithelial tissues and plays a role in maintaining cellular architecture and tissue integrity. This glycoprotein contributes to the organization of cell-cell junctions, which are critical for epithelial barrier function and communication between cells. Altered expression of SMAGP has been observed in various cancers, including gastric and colorectal cancers, where it may influence tumor progression and metastasis by affecting cellular adhesion and epithelial-to-mesenchymal transition (EMT). Research into SMAGP continues to explore its functional mechanisms in epithelial biology and its potential as a biomarker for cancer diagnosis and prognosis. By providing insights into the molecular pathways governing cell adhesion and tumorigenesis, studies on SMAGP contribute to the broader understanding of cancer biology and therapeutic opportunities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Small cell adhesion glycoprotein; small cell transmembrane and glycosylated protein; small trans-membrane and glycosylated protein; Small transmembrane and glycosylated protein
基因别名: hSMAGP; SMAGP
UniProt ID: (Human) Q0VAQ4
Entrez Gene ID: (Human) 57228
