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This peptide corresponds to 14 amino acids near the carboxy terminus of human of SQSTM1.
PEP-0953 can be used as a blocking peptide with polyclonal antibody PA5-20839.
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; oxidative stress induced like; phosphotyrosine independent ligand for the Lck SH2 domain p62; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Sequestosome-1; Ubiquitin-binding protein p62
基因别名: A170; FTDALS3; ORCA; OSIL; p60; p62; p62B; PDB3; SQSTM1; ZIP3
UniProt ID: (Human) Q13501
Entrez Gene ID: (Human) 8878