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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51922. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SG2NA was identified as a human cancer autoantigen and has now been implicated in vesicular trafficking and signal transduction. It is highly related to striatin and zinedin. It is a scaffolding protein that binds PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which has been implicated in control of mitotic progression in yeast. It also binds calmodulin and appears to modulate PP2A activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen; nuclear autoantigen; protein phosphatase 2 regulatory subunit B'''beta; S/G2 antigen; striatin, calmodulin binding protein 3; Striatin-3
基因别名: GS2NA; PPP2R6B; SG2NA; STRN3
UniProt ID: (Human) Q13033
Entrez Gene ID: (Human) 29966