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Highest antigen sequence indentity to the following orthologs: Mouse (50%), Rat (50%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56466. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC119154; MGC119155; T2R56; T2R60; Taste receptor type 2 member 56; Taste receptor type 2 member 60; taste receptor, type 2, member 60
基因别名: T2R56; T2R60; TAS2R60
UniProt ID: (Human) P59551
Entrez Gene ID: (Human) 338398