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产品信息
PEP-0175
产品规格
种属反应
Human
宿主/亚型
Artificial Control
分类
Synthetic
类型
Peptide
偶联物
Unconjugated
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 16 amino acids from the middle of human TLR8.
PEP-0175 can be used as a blocking peptide with polyclonal antibody PA5-20056.
靶标信息
The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
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生物信息学
蛋白别名: CD antigen 288; CD288; Toll-like receptor 8
基因别名: CD288; TLR8; UNQ249/PRO286
UniProt ID: (Human) Q9NR97
Entrez Gene ID: (Human) 51311
