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Invitrogen
Human TRAM2 (aa 46-75) Control Fragment Recombinant Protein
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产品信息
RP-103312
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
AFLFILPQYNISVPTADSETVHYHYGPKDL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63503. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: TRAM-like protein; Translocating chain-associated membrane protein 2
基因别名: KIAA0057; TRAM2
UniProt ID: (Human) Q15035
Entrez Gene ID: (Human) 9697
