Invitrogen

Human TSPY1 Synthetic Peptide

说明书

技术支持

说明书

技术支持

产品信息

PEP-1525

应用

建议稀释比

已发表文章

对照试剂 (Ctrl)

Assay-dependent

阻断反应 (BLOCK)

Assay-dependent

产品规格

种属反应

Human

分类

Synthetic

类型

Peptide

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

purified

保存液

PBS, pH 7.2, with 0.1% BSA

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Dry ice

产品详细信息

This peptide corresponds to 20 amino acids near the carboxy terminus of human TSPY1L.

PEP-1525 can be used as a blocking peptide with polyclonal antibody PA5-34483.

靶标信息

Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.

仅用于科研。不用于诊断过程。未经明确授权不得转售。