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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52316. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Thiosulfate:glutathione sulfurtransferase (TST) required to produce S-sulfanylglutathione (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed:24981631). Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide:quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate (PubMed:24981631). The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor (PubMed:24981631). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: putative thiosulfate sulfurtransferase KAT; thiosulfate sulfurtransferase (rhodanese)-like domain containing 1; thiosulfate sulfurtransferase KAT, putative; Thiosulfate:glutathione sulfurtransferase; TST
基因别名: KAT; TSTD1
UniProt ID: (Human) Q8NFU3
Entrez Gene ID: (Human) 100131187