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Invitrogen
Human VEGF-121 Recombinant Protein
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产品信息
RP-8646
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
形式
Lyophilized
浓度
0.1 mg/mL
Amount
10 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Recombinant human VEGF-121 is a non-glycosylated homodimer, containing two 121 amino acid chains , with a total molecular weight of 28.4 kDa. Purity is typically greater than 95% and endotoxin level less than 1 EU/ug.
The expected biological activity (ED50) is determined by the dose-dependent proliferation of HUVECs and is typically 1-6 ng/mL. The specific activity of this protein is 1x10^6 units/mg.
Reconstitute using sterile water at 0.1 mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability.
Amino acid sequence: APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENCDKPR R.
靶标信息
Vascular Endothelial Growth Factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability, VEGF-A may play a role in stimulating vasodilation via nitric oxide-dependent pathways. Mouse VEGF-A has several variants, one being VEGF-120. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95%.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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