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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).^M
^M
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111550. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein Wnt-10b; Protein Wnt-12; wingless-type MMTV integration site family member 10B; wingless-type MMTV integration site family, member 10B; WNT-10B protein
基因别名: SHFM6; WNT-12; WNT10B; WNT12
UniProt ID: (Human) O00744
Entrez Gene ID: (Human) 7480